The big 3 to beat DHT, THE CAUSE OF HAIRLOSS!

- Propecia ( Finesteride ), Minoxodil and Nizoral

Here is the thing you need to make sure you understand when it comes to MPB:

The main known factor that causes hairloss is DHT. To form DHT your body's 5a-reductase enzyme converts free roaming testosterone DHT inside the hair cell follicle. The DHT then binds to the hair cell receptor and causes it to atrophy or shrink. Eventually your hair follicle stops producing hair and you lose that follicle.

There are two types of the 5ar enzyme; Type I and Type II. Type II 5ar seems to be the main culprit in MPB as the type II enzyme is present in the hair follicles. Finasteride is a specific inhibitor of Type II 5ar inhibitor that reduces DHT produced by the type II 5ar by 85%-90% and reduces the overall DHT blood serum levels by 65%.

As you can see Finasteride (PROPECIA ) is extremely useful as a treatment for MPB as it directly attacks the problem. Nizoral shampoo is thought to help "dull" the androgen receptors in the scalp which the DHT binds to. Together they provide a synergetic effect.

Minoxidil is a hair stimulant. It is the only FDA proven hair stimulant on the market. However stimulating hair and protecting hair from further damage are two separate actions

Minoxidil will artificially augment your hair while you use the compound but it does NOT have any know effect on 5ar or the androgen receptors in the scalp.

The best way to attack MPB is to:

1. Stop further damage to your hair via DHT. You can accomplish this best by using Finasteride to inhibit the 5ar enzyme and Nizoral to "dull" the androgen receptors.

2. **If** further thickening/regrowth is needed after the hair damaging DHT androgen is reduced then minoxidil can be used to further augment your existing hairs and perhaps even stimulant some dormant hair follicles to resume growing.
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Regards
Specs

Agree with Specs

The big 3 are the one's to go for.

However I also use Zinc and take twice the daily recommended RDA.

Makes hair and nails grow fast.

Anyway it works for me.

Joe90

Big 3 works for me also.

Will give the zinc a try only read good stuff about it.


RonnieF

Hello im 18 and a male . i suffer from serious dandruff which has always plagued my scalp and im looking for some help.But now instead when i sweat , my scalp becomes sore . it then turns a burning red which is resulting in a huge amount of hairloss. i have tried evry anti - dandruff shampoo but nothng has helped the condition . it just seems to get worse. i would greatly appreciate any help .

Dia - i would recommend you see you GP about your situation - your situation could be a reaction to one of the shampoos you've been using.

Hey there everyone. i have decided to start using rogaine but i am 17, and the packet says u should be 18, i simply cannot wait to be honest as my hair loss is getting rather bad now, and styling my hair to cover it is beginning to fail. i also know that rogaine takes a few months to work anyway so am i being really stupid here or what? what do you recommend anyone? joe

Hi Diarmuid and Welcome

As specs says you should see your doctor.

Use one shampoo for a couple of weeks to see if that particular product is causing the problem.

This is a process of elimination to see whether one particular product affects you.

I would recommend starting with Nizoral, just follow the directions.


Bill

Thanks for the replies.Regarding Nizoral , I've tried it so many times but it seems useless, as it only seems to make the scalp red and sore .From having bad dandruff , the follicles now seem to be changing , some hairs are now extremely thin , while some hairs are unusually hard.If the dandruff situation was resolved ,would having lengthy hair cover or stop follicles from growing hair?Just a question! So I've run out of ideas and any help would be greatly appreciated.

sonds like you've over used the nizoral shampoo! its very strong stuff and only meant to be used 2 x a week! if i were you i would stop using it for a while and allow your head to return to some state of norm before embarking on any other meds

Is Minoxodil supposed to make your heart beat faster? Or maybe I'm just paranoid but I've been getting tired a bit faster than usual ever since I started taking it... maybe I should just check a doctor out before something bad happens.. ahh

add some MSM to the big three combo guys - makes your hair grow very quickly as well as making it stronger. - all good!

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nornam - you could just try applying it once - at night

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what is MSM ?

MSM -
Some of MSM's essential functions in the body include maintaining the structure of the proteins in the body, helping the formation of keratin which is essential for hair and nail growth, aiding in the production of immunoglobulin which maintains the immune system, and catalyzing the chemical reactions which change food into energy.

These functions often result in the following occurrences:

Inhibition of pain impulses along nerve fibers (analgesia)
Lessening of inflammation
Increase in blood supply
Reduction of muscle spasm
Softening of scar tissue


I take 3000 mg a day and it has increase the speed of my hairs growth and given it an overall thicker healthier look.

You can easily get it for Holland and Barrett

Regards
specs

Thanks spec. You know soo much about hairloss. I do have another question, when you speak of the big 3 combatting hairloss - is there some kind of an order? Should you use Nizoral, Finerasteride and minoxidil together? or only use Nizoral and Finerasteride and then Minoxidil at some point in the future? Is it okay to use all three products together?

Use all these 3 products together -

1. Minoxidil 2 x a day - once in the am and once in the pm
2. Finesteride (propecia/proscar) 1mg per day
3. Nizoral 2 x a weeks (no more) - will dry your scalp out!

all the best
specs

Hi there,
I'm new to the website. A bit about myself first to give a background. I'm a 26 year old male of 6'2" and weight 14.7 stone. I do a lot of exercise including weights, martial arts etc. In the last few years I've become thinner on top to a point where it is noticable. I've been using extra strength regaine, which is the Minoxodil solution. I've been pretty regularly appying this for 8 months now and seem to be getting no where. I'm desperate to replace my hair to the point that I'm considering hair implant although the cost is the biggest downfall. Can anyone suggest techniques that will definately help with rough success rates. I currenly have about 5 months supply of minoxodil and am prepared to pay up to £150 for any initial treatment. I've read all the reviews on the BIG3, but how effective is it and where do I start?

Regards,

JC

you can look on this site for the big three,
and try that <proscra.minoxodil.and nizoral>
it may help

Thanks Specs!! The only problem is that i find that when using Minoxidil it really dry's my hair out and my hair becomes extra wavy - meaning that it becomes very difficult to style! Above all, the hair seems to drop out even more and my pillow is always full of hair when i wake up in the morning.

ohh well...

1 more question, i went to boots a few days back - there were a few Nizoral shampoo's which one is the correct one?

RP

The right stuff!

Specs,
I have visited your website and as you'll see have just ordered 6 months of the propecia as I already have the other two items for the big 3. I've also ordered some MSM and zinc tablets hoping that all five items will complement each other? I understand you are very knowledable with regards to MPB and I have one question that you may be able to answer. I understant that the DHT is a bi-product of Testosterone and that is effectively strangles the hair follicles? I also understand that anyone who is heavily into sports etc is more likely to increase their levels of testosterone. By increasing the levels of testosterone, would this also likely increase the levels of DHT do you think?

Any help would be much appreciated as I am heavily into sports and weights and am worried this may increase my DHT production?

Regards,

Jordon

Appologies to Specs, I thought I'd ordered propecia off you the other week, somehow I ended up ordering procerin from a completely different website - I honestly don't know how this happened. Anyway I'm gonna give it a try now that it's here and see if there's any difference in a few months, I will report any results to you all if there are some. If there's no results, can I order some off you specs or do I have to see my doctor first?

Regards,

JPC

specs is still away so can't respond but he doesn't sell anything he can put you in touch with his GP Dr Ashcroft hho can perscribe proscar to you(sound guy)

the stuff you have is not any good in my opinion and you should get on proscar/propecia asap if your wanting to do the best thing possible
g

Hi,

I'm new here, but was just wondering;
Why you are recommending Finasteride/Propecia as part of the 'big three' treatment, when Avodart (although not yet licensed specifically for hair loss) seems to be a much better drug for suppressing 5ar enzymes..?

Any reason not to use it (especially when it can even work out cheaper per dose than Propecia)?

Thanks

You need to reduce inflammation in the scalp tissue and increase microcapillary circulation. As well as finasteride, I use retin A cream with the minoxidil and golden emu oil to reduce inflammation, then in the evening after shampoo with Nizoral, I use the laser comb
(which has had good reports on NBC) and my own device for increasing microcapillary circulation. After twenty years of what seemed like fully developed shiny mpb, 14 months of this combined treatment (plus a range of herbal and hormone supplements) has produced thousands of new terminal hairs springing into life)
It is the combination of all the available approved medications and treatments which does the trick. Specs and others have helped me to understand some aspects of the DHT process, but the science is rather incomplete. I succeeded by guesswork and experimentation. I am amazed that each week and month I have some longer hairs to brush. The feeling of the hairs interacting and springing back is incredible. It may take another year or two to get an even appearance, but now I am looking forward to my 50th birthday, as I will look better than at 40!
Ulsterman

sounds like things going well for you mate, you say your having hair regrowth, is your hair regrowth quite thick

Hi Specs,
I've taken your advise on the Big 3 along with taking msm and zinc tablets daily. By using the Big 3, what are the results likely to be over time? Am I likely to regrow all or most of what hair has been lost or are the results only slight? I am currently thinning on top and at the back and am hoping with time that these treatments will help restore what has been lost.

Please advise

Regards,

JPC

Everyone responds differnetly to treatment but generally if you've caught your hairloss in the early stages chances are you will stop further loss and recover a great deal of ground.

Trick is to not scrutinize over your hair - continue with the big 3 for at least 6/8 months to see significant results.

Important :You must remain on the meds to maintain your results.

Regards
specs

Hey guys I am new to this site and just wanted some advice. I currently use all of the 3 we are talking about but the propecia I use is fincar..Are these the same stuff or am I wasting my time? If so where can I get a cheap alternative as Iam a student and strapped for cash.

Also one last question, Does anyone know of any hair thicking shampoo's that are worth a try..ive heard some of these are pretty good.

Thanks for your time,

Kris

Hello, I just turned 16 and I have had long hair for 3 years. I have noticed hair loss for about two years and now it is beginning to get quite thin. My GP sent me to a dermatoligist. After ordering blood test to rule out any possible health problems, which came back okay, the dermatoligist diagnosed me with having male pattern hair loss. He told me to take biotin 2.5mg daily (I am taking a multi-vitamin as well), because the b-vitamins work together. He said it would take 3-4 months for me to notice anything. Then he told me I could use Rogain but I am having doubts because of the side effects. Any advise on any products that could be fast, safe, effective and useful?

Justin

Kris Kelly - the best option is to take the legitemate product as fincar is a little hit and miss i believe.

Good thickening shampoos on the site

www.hair123.co.uk

Justino -

There is NO quick fix - your best option due to your age is keep with the natruals and hold off the propecia and minox as you are too young.

spex what shampoo do you use?

I use Nizoral 2 x a week and then just an everyday shampoo

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should it not be the big 4 now with this new caffine shampoo?

I would recommend alternating the shampoos - but any defense against DHT the better!!

Spex,

Where did you hear that Fincar was 'hit and miss'? I take Finpecia (i.e. Cipla's 1mg version of Fincar) from ( Edited - No links to priscition drug sites allowed ) and I've certainly had effects from it (of the side variety ) and my next order was probably going to be Fincar as its so bloomin cheap, but I'd be interested in any info that suggests that it isn't proper finasteride.

Oh and a vote for copper peptides!

If you are to believe Fincar is what it says it is, then yes it should be just as good.

Just keep in mind the drug comes from a country that is known to export large amounts of fake drugs...

where's it come from? Is it India?

There are several issues here!

India has a reputation for making generic drugs not fake drugs - I am sure that lots of countries (including the US and UK) have people producing fake drugs in them..and, to be honest, with regards to finasteride, I'd be more concerned that my branded Proscar/Propecia is fake than my generic Fincar/Finpecia is - simply because of the profitability factor - the cheapest I have seen Proscar is £39 ( Edited - No links allowed to prescition drug sites ) whilst the cheapest I have seen Fincar is £17.

It's the resellers who are the concern with regards to fake drugs and hence why it's important to mention where you buy your finasteride from. I buy my Finpecia from ( Edited - No links allowed to prescition drug sites ) and I'd do the same if I got Fincar, whilst the cheapest Proscar seems to be ( Edited - No links allowed to prescition drug sites ) - which has been mentioned a few times on HLT and HLH as reputable. I've seen ( Edited - No links allowed to prescition drug sites ) mentioned a few times as well.

Obviously if you can afford to get branded Propecia from your local chemist then that would be the best, but at £32 (from Asda) for 28, its expensive!

Whether generic drugs are as good as branded drugs is a moot point - Indian laws state that their manufacturing companies (such as Cipla) can produce patented drugs as long as the manufacturing process is different - good news price-wise, but people do get concerned about whether the finasteride in Cipla stuff is as good as the finasteride in Merck's pills, but the company's long (and good) reputation for produding generics and other people's reports are enough to convince me. I certainly don't consider the manufacturers country as a huge factor - Merck branded stuff is made in all sorts of places! I guess people just have to research it themselves and make their own mind up..

Hi Watery Jizm

This is out of my hands.

It is a UK thing and I have had problems with trading standards before, so I have to careful.

Bill

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Spex im coming up to 32 years of age now and im debating starting the big 3.However my only concern is that once I start I will have to continue this for the rest of my life.Financially it is not a problem is more a concern over health obviously you are taking them how do you look at this matter.

I have been on propecia for 7 yrs and its held me solid - i used to use Minox but no longer. i still wash my hair with nizoral 2 x a week but not religiously.
It comes down to how much you want to try to prevent your hairloss.
I know a number of guys who have been on meds much longer than i have with no health issues so this installs confidence in me but to be honest i wish i didn't have to take propecia but i must in order to manitain.

Each to their own i suppose mate but only recently a 10 year study was conducted on Propecia by Merck (the makers) and on all accounts it was good news.

Thanks spex I really do find your wealth of experience on transplants a great help.Im getting married later this year but I think I will have to arrange to meet you end 2006/beginning2007.

Glad i can help you out MCS. More than happy to hook up in the future All the best!

Guys what is this cafien shampoo?
Does it really work?

and I understand that Finasteride works by targeting the 5 AR, is there anything which gets rid of the DHT and not just stops it from producing??

Thanks