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Hair Follicle Stem Cells Contribute To Wound Healing


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#1 stophair

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Posted 31 December 2005 - 10:54 AM

Hair Follicle Stem Cells Contribute to Wound Healing, According to New Penn Study

Implications for Skin Problems Related to Diabetes and Other Disorders

(Philadelphia, PA) - Hair follicle stem cells are important contributors to the wound-healing process, according to new research by investigators at the University of Pennsylvania School of Medicine.

Using an animal model, the researchers discovered that stem cells in the hair follicle are enlisted to help heal wounds in the skin. This finding, published online in Nature Medicine last week, may suggest a therapeutic target for the development of drugs to encourage and promote wound healing.

Wounds, including skin ulcers and other dermatological problems associated with diabetes, circulatory problems, and other diseases, are a growing medical problem in the United States, notes senior author George Cotsarelis, MD, Associate Professor of Dermatology.

Previous work by the Penn research team had outlined the hair-growth process to show that stem cells in the hair follicle "bulge" area generate new lower hair follicles, which in turn, generate new hair.

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